Publications

2022

Rai M., Carter SM§, Shefali SA, Mahmoudzadeh NH, Pepin R, Tennessen JM. (2022). The Drosophila melanogasterenzyme glycerol-3-phosphate dehydrogenase 1 is required for oogenesis, embryonic development, and amino acid homeostasis. G3 Genes|Genomes|Genetics, 2022;, jkac115, https://doi.org/10.1093/g3journal/jkac115

Taub M., Mahmoudzadeh NH, Tennessen JM, Sudarshan S. (2022). Renal Oncometabolite L-2-Hydroxyglutarate Imposes a Block in Kidney Tubulogenesis: Evidence for an Epigenetic Basis for the L-2HG Induced Impairment of Differentiation. In Revision.

Parish AJ, Rice DW, Tanquary VM, Tennessen JM, Newton ILG. (2022). A honey bee symbiont buffers larvae against nutritional stress through lysine supplementation. bioRxiv 2022.01.11.475899 

Yang S, Niou ZX, LaMar J, Enriquez A, Huang JY, Tennessen JM, Rangaraju V, Lu HC. (2022). NMNAT2 is the major NAD+ provider for vesicular glycolysis generating on-board energy for fast axonal transport cargos. bioRxiv 2022.02.06.479307

2021

Tennessen JM. (2021). Ecdysone and 20-hydroxyecdysone are not required to activate glycolytic gene expression in Drosophila melanogaster embryos. Micropublications Biology. 2021:10.17912/micropub.biology.000501.

Pandey M, Bansal S, Bar S, Sokol NS, Tennessen JM, Kapahi P, Chawla G. (2021). miR-125-chinmo pathway regulates dietary restriction dependent enhancement of lifespan in Drosophila. eLife. 10:e62621.

2020

Mahmoudzadeh N, Fitt A§, Schwab DB, Brinkley GJ, Martenis N§, Neese L, Li H, Owings CG, Karty JA, Hardy RW, Moczek AP, Sudarshan S, Picard CJ, and Tennessen JM. (2020). Dipteran larvae accumulate high levels of the oncometabolite L-2-hydroxyglutarate. Insect Biochemistry and Molecular Biology. 127:103493

Luhur A, Mariappa D, Klueg KM, Buddika K, Tennessen JM, Zelhof AC. (2020). Adapting Drosophila melanogastercell lines to serum-free culture conditions. G3:Genes|Genomes|Genetics. 10(12):4541-4551.

Brinkley G, Nam H, Shim E, Kirkman R, Kundu A, Karki S, Heidarian Y, Tennessen J, Liu J, Locasale J, Guo T, Wei S, Gordetsky J, Johnson-Pais T, Absher D, Rakheja D, Kumar Challa A, and Sudarshan S. (2020). Teleological Role of L-2-Hydroxyglutarate Dehydrogenase in the Kidney. Disease Models and Mechanisms. dmm045898.

Bawa S, Brooks DS, Neville KE, Tipping M, Sagar MA, Kollhoff JA, Chawla C, Geisbrecht BV, Tennessen JM, Eliceiri KW, and Geisbrecht ER. (2020). Drosophila TRIM32 cooperates with glycolytic enzymes to promote cell growth. eLife. 9:e52358.

2019

Li H, Rai M, Buddika K, Sterrett MC, Luhur A, Mahmoudzadeh NH, Julick CR, Pletcher RC, Chawla G, Gosney CJ, Burton AK, Karty JA, Montooth KL, Sokol NS, Tennessen JM. Lactate dehydrogenase and glycerol-3-phosphate dehydrogenase cooperatively regulate growth and carbohydrate metabolism during Drosophila melanogaster larval development. Development. pii: dev.175315. doi: 10.1242/dev.175315.

Li H, Tennessen JM. (2019). Quantification of D- and L-2-Hydroxyglutarate in Drosophila melanogaster Tissue Samples Using Gas Chromatography-Mass Spectrometry. Methods Mol Biol. 1978: 155–165. doi:10.1007/978-1-4939-9236-2_10.

Pletcher RC, Hardman SL, Intagliata SF, Lawson RL, Page A, Tennessen JM. (2019). A Genetic Screen Using the Drosophila melanogaster TRiP RNAi Collection To Identify Metabolic Enzymes Required for Eye Development. G3: Genes | Genomes | Genetics. 9(7):2061-2070. doi: 10.1534/g3.119.400193.

Krejčová G, Danielová A, Nedbalová P, Kazek M, Strych L, Chawla G, Tennessen JM, Lieskovská J, Jindra M, Doležal T, and Bajgar A. (2019). Drosophila macrophages switch to aerobic glycolysis to mount effective antibacterial defense. eLife. 8:e50414.

2018

Li H and Tennessen JM. (2018). Preparation of Drosophila larval samples for gas chromatography-mass spectrometry (GC-MS)-based metabolomics. Journal of Visualized Experiments. 136: e57847. https://doi.org/10.3791/57847

Li H, Hurlburt AJ, and Tennessen JM. (2018). A Drosophila model of combined D-2- and L-2-hydroxyglutaric aciduria reveals a mechanism linking mitochondrial citrate export with oncometabolite accumulation.  Disease Models and Mechanisms. 11(9): dmm035337. https://doi.org/10.1242/dmm.035337

Osburn, K., Amaral, J., Metcalf, S. R., Nickens, D. M., Rogers, C. M., Sausen, C., … Bochman, M. L. (2018). Primary souring : A novel bacteria-free method for sour beer production. Food Microbiology, 70, 76–84. https://doi.org/10.1016/j.fm.2017.09.007

2017

Clair, S. L. S., Li, H., Ashraf, U., Karty, J. A., & Tennessen, J. M. (2017). Metabolomic Analysis Reveals That the Drosophila melanogaster Gene lysine Influences Diverse Aspects, 207(December), 1255–1261. https://doi.org/10.1534/genetics.117.300201/-/DC1.1

Krejci, A., & Tennessen, J. M. (2017). Metabolism in time and space – exploring the frontier of developmental biology, 3193–3198. https://doi.org/10.1242/dev.150573

Li, H., & Tennessen, J. M. (2017). Methods for studying the metabolic basis of Drosophila development, 6(October). https://doi.org/10.1002/wdev.280

Zhang, W., Ogando, D. G., Kim, E. T., Choi, M., Li, H., Jason, M., & Bonanno, J. A. (2017). Endothelial Cell Line Recapitulates Disrupted. https://doi.org/10.1167/iovs.17-21781

Cox, J. E., Thummel, C. S., & Tennessen, J. M. (2017). Metabolomic Studies in Drosophila, 206(July), 1169–1185.

Li, H., Chawla, G., Hurlburt, A. J., Sterrett, M. C., Zaslaver, O., & Cox, J. (2017). Drosophila larvae synthesize the putative oncometabolite L-2-hydroxyglutarate during normal developmental growth, 114(6), 2–7. https://doi.org/10.1073/pnas.1614102114

Zhang, W., Li, H., Ogando, D. G., Li, S., Feng, M., Price, F. W., … Bonanno, J. A. (2017). EBioMedicine Glutaminolysis is Essential for Energy Production and Ion Transport in Human Corneal Endothelium. EBioMedicine, 16, 292–301. https://doi.org/10.1016/j.ebiom.2017.01.004

Previous (selected)

Tennessen, J. M., Barry, W. E., Cox, J., & Thummel, C. S. (2014). Methods for studying metabolism in Drosophila. Methods, 68, 105–115. https://doi.org/10.1016/j.ymeth.2014.02.034

Tennessen, J. M., Bertagnolli, N. M., Evans, J., Sieber, M. H., Cox, J., & Thummel, C. S. (2014). Coordinated Metabolic Transitions During Drosophila Embryogenesis and the Onset of Aerobic Glycolysis, 4(May), 839–850. https://doi.org/10.1534/g3.114.010652

Tennessen, J. M., & Thummel, C. S. (2011). Coordinating growth and maturation - Insights from Drosophila. Current Biology, 21(18), R750–R757. https://doi.org/10.1016/j.cub.2011.06.033

Tennessen, J. M., Baker, K. D., Lam, G., Evans, J., & Thummel, C. S. (2011). Article The Drosophila Estrogen-Related Receptor Directs a Metabolic Switch that Supports Developmental Growth. Cell Metabolism, 13(2), 139–148. https://doi.org/10.1016/j.cmet.2011.01.005

Palanker, L., Tennessen, J. M., Lam, G., & Thummel, C. S. (2009). Article Drosophila HNF4 Regulates Lipid Mobilization and b -Oxidation. Cell Metabolism, 9(3), 228–239. https://doi.org/10.1016/j.cmet.2009.01.009